Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individuals lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances
This book focuses on the similarities and differences between substance and non-substance addictions. It discusses in detail the mechanisms, diagnosis and treatment of substance and non-substance addictions, and addresses selected prospects that will shape future studies on addiction. Addiction is a global problem that costs millions of lives tremendous damage year after year. There are mainly two types of addition: substance addiction (e.g., nicotine, alcohol, cannabis, heroin, stimulants, etc.) and non-substance addiction (e.g., gambling, computer gaming, Internet, etc.). Based on existing evidence, both types of addiction produce negative impacts on individuals physical, mental, social and financial well-being, and share certain common mechanisms, which involve a dysfunction of the neural reward system and specific gene transcription factors. However, there are also key differences between these two types of addiction. Covering these aspects systematically, the book will provide researchers and graduate students alike a better understanding of drug and behavioral addictions. Dr. Xiaochu Zhang is a professor at the School of Life Sciences, University of Science and Technology of China, and a principal investigator at the Cognitive Neuropsychology Lab. His research focuses on the neural basis of drug and behavior addiction and its applications to addiction treatment. He has published more than 30 articles in international peer-reviewed journals. Dr. Jie Shi is a principal investigator and Associate Director of the National Institute on Drug Dependence, Peking University. She is also vice chairwoman of the Drug Dependence Branch of the Chinese Society for Toxicology (CST) and a committee member of the physiopsychology branch of the Chinese Psychological Society. Her research focuses on neural imaging of patients with drug addiction and clinical pharmacology. Dr. Shi has published more than 40 research articles in these fields. Dr. Ran Tao is a chief physician and director of the Internet Addiction Treatment Center, General Hospital of Beijing Military Region. He is also chairman of the Beijing Shijian Integrated Medicine Science Institute and director of the Adolescent Psychological Development Base in China. His research focuses on addiction biology, especially Internet addiction, and he has published several articles in this field.